PROTACs: Targeting breakdown of specific proteins to treat diseases
Felicites Rapon explores the advantages of PROTACs over small molecule inhibitors in addressing cancer treatment and drug resistance.
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The legacy of a girl who inspired a “holy grail” cancer-killing pill
Niamh Walker reports on the recent development of AOH1996, a pill targeting cancerous cells, offering a new approach to cancer treatment.
When size matters: New research strategies targeting cancer cells
Lola Bell reports on a new study suggesting the size of cancer cells could become a new diagnostic for directing treatment.
Checkpoints: Progress in cancer immunotherapy
Cecilia Jay describes the challenges facing immunotherapy as cancer treatment, and its potential to revolutionise personalised medicine .
Innate-like T-cells: a New Weapon in Cancer Immunotherapy?
New research has found a novel population of T-cells that may be more successful than current immunotherapy treatments at targeting cancer cells. James O’Brien discusses.
The War Against Cancer – Are Our Bodies Our Own Greatest Weapons?
Over the last few decades, our treatment of cancer has been revolutionised. The field has been transformed by a focus on ‘personalised medicine’ which involves treating patients’ individual cases rather than grouping them together. It is universally recognised that there is no single cure for cancer, and increasing evidence suggests that there is not a…
![Image from: Jonathan Bailey / NHGRI [CC BY-SA 4.0 (https://creativecommons.org/licenses/by-sa/4.0)], via Wikimedia Commons](https://i0.wp.com/oxsci.org/wp-content/uploads/2018/12/Circulating-tumor-dna_image.jpg?resize=600%2C400&ssl=1 "A 10-minute, universal blood test for cancer")
A 10-minute, universal blood test for cancer
Researchers at the University of Queensland, Australia have developed a blood test that can detect whether a patient has any type of cancer within as little as 10 minutes. Although still in the initial stages of testing, this cheap and simple method could help clinicians to diagnose cancer before symptoms appear, when the widest range…
Missing Cancer Puzzle Piece: Could Interstitium Be the Answer?
A group of researchers has discovered that the interstitial space surrounding cells in numerous tissues such as the lungs, gut, dermis and blood vessels has a unique structure that hasn’t been described before. It has been observed that this space is made up of multiple fluid-filled sinuses that form a network through which interstitial fluid…
Research finds promising technique to combat cancer drug resistance
Multi-drug resistance is the main challenge for chemotherapy – it is the leading cause of tumour recurrence and cancer metastasis. The root of the problem: efflux pumps on the cell surface which serve to protect a cell by pumping out unwanted toxic substances. Unfortunately, these come as a disadvantage when targeting cancer cells with drugs….