iGEM: Using synthetic biology to cure autoimmune diseases

iGEM is an international competition where teams of university students compete in designing a genetically engineered product to tackle a world problem. Oxford’s iGEM team for 2018 is made up of 10 undergraduate students who study a range of subjects including biochemistry, biology, chemistry, engineering and medicine. After a long process of designing and planning…

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Oxygen: a Load of Pure Phlogiston?

By Alexander James, Sir John Deane’s College, Cheshire Oxygen is vital to life and is used in numerous industrial processes. However, there was a time when the existence of oxygen as a concept, let alone as an element, was completely unknown. One of the early scientific theories of combustion was called the Phlogiston Theory, developed…

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Could Suspended Animation Change the Future of Accident & Emergency?

By Banda Chisomo, King Edward IV Five Ways School, Birmingham Picture this: a patient has a large gunshot wound to their lower abdomen and they had excessive haemorrhaging before suffering from myocardial infarction and flatlining. They are rushed to the accident and emergency ward where the doctors assess the extent of the damage and they…

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Kepler’s Discovery

by Ivan Komarov, Wellington College, Berkshire While Copernicus and Galileo often receive the credit for their ideas, it was Johannes Kepler (1571-1630) who discovered and demonstrated that the Earth orbits the Sun. In his 1609 work, “The New Astronomy”, Kepler destroyed the Aristotelian cosmography of perfect forms and unknowable causes, forever changed man’s sense of…

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TRAPPIST-1: Are We Alone in the Universe?

By Natalie Stevenson, Sandbach High School and Sixth Form College, Cheshire There has been one question which has plagued humankind throughout possibly the entirety of history – are we alone in the Universe? Although we still might not have the answer, advances in technology and space exploration has meant that we are slowly edging closer…

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Clonal Selection Theory—An Immunological Breakthrough

By Stella Stylianides Da Silva, James Allen’s Girls’ School, London We owe a great deal for our current understanding of the immune system to a theory developed in 1957. The clonal selection theory for the formation of antibodies is considered the most important discovery in immunology in the last 100 years. In his paper “A…

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Missing Cancer Puzzle Piece: Could Interstitium Be the Answer?

A group of researchers has discovered that the interstitial space surrounding cells in numerous tissues such as the lungs, gut, dermis and blood vessels has a unique structure that hasn’t been described before. It has been observed that this space is made up of multiple fluid-filled sinuses that form a network through which interstitial fluid…

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