A group of researchers has discovered that the interstitial space surrounding cells in numerous tissues such as the lungs, gut, dermis and blood vessels has a unique structure that hasn’t been described before. It has been observed that this space is made up of multiple fluid-filled sinuses that form a network through which interstitial fluid…
Multi-drug resistance is the main challenge for chemotherapy – it is the leading cause of tumour recurrence and cancer metastasis. The root of the problem: efflux pumps on the cell surface which serve to protect a cell by pumping out unwanted toxic substances. Unfortunately, these come as a disadvantage when targeting cancer cells with drugs….
“The rabbit-hole went straight on like a tunnel for some way, and then dipped suddenly down, so suddenly that Alice had not a moment to think about stopping herself before she found herself falling down what seemed to be a very deep well.” – so reads one of the many literary quotes shared by Oxford’s…
The current UK population consumes an average of about 8.5g/day of salt, more than 2g/day above the maximum recommended daily amount. This is worrying given its well-known health implications. Salt raises blood pressure, increasing risk of heart disease and stroke. One in three of UK adults have high blood pressure, and as many people are…
Oxford University and Public Health England (PHE) have lead an international team of scientists in an analysis of HIV migration patterns across the Ukraine. This study, which used genomic data to reconstruct the spread of the virus, has shown how geopolitical events have helped to conduct the virus to regions where it is more likely…
When we experience a particularly bad flu season, like the current one, the question of how a single disease can vary so wildly is often raised. The answer lies in the simple fact that the virus copies its RNA genome with very poor accuracy which means that the virus is constantly mutating and evolving to…
Members of the Oxford Department of Zoology have tracked peregrine falcons in the field as they attacked dummy prey – and discovered that they use the same control strategies to catch them as modern projectile weapons. This suggests a new way to tackle the problem of rogue drones. Principle investigator Professor Graham Taylor said “Falcons…
Alzheimer’s disease is a major global health problem, with the number of people with the disease in the UK expected to double by 2050. Efforts to develop an effective treatment have not yet been successful as we don’t properly understand what causes it. What do we already know about Alzheimer’s? One of the key features…
It is understood that climate change will lead to increased humidity, but why should we care? The reason is that heat stress, which is set to become a prominent and pressing issue as global temperatures rise, is compounded by humidity. Materials provided by The Earth Institute at Columbia University explain that it is more difficult…
A recent study, published on Nature Neuroscience, lays groundwork for potential development of first neurobiologically-based therapy for patients with autism spectrum disorders (ASD). This research from the O’Donnell Brain Institute in the U.S. explored a specific area within the right cerebellum, called CrusI. Whilst cerebellar abnormalities in ASD patients were known for some time, the…
