Personalised Medicine

What happens when one size does not fit all? The first race-based combination prescription drug, Hydralazine-plus-nitrate is used in the treatment of congestive heart failure. Among African Americans, life expectancy of those with heart failure is increased using this combination drug, whereas white Americans respond less effectively to the drug. Another drug, Gefitinib, used in…

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Collaboration: Reforming Research

Most researchers’ response to the word ‘collaboration’ is overwhelmingly positive. Many of the most influential scientific breakthroughs that have gone on to shape today’s scientific landscape have been the product of collaborations: Gates and Allen, the Wright brothers, and Watson, Crick and Franklin, to name a few. The global value of collaboration can be seen…

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Wild Things – a review

‘Wild Things’ is the latest venture from The House of Improv. In this improvised comedy, the team address human interactions with an endangered animal which is conjured out of thin air by the audience. In the Tuesday performance, this animal was the creaky-tailed hippopotamus. Set in Creaky-Tailed Hippopotamus Town, the play followed the stories of…

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Ramakrishnan and his ribosome – a review

Venki Ramakrishnan, President of the Royal Society and 2009 Nobel Prize winner, is already well known in the scientific community for his publications about the ribosome. What I wasn’t expecting however, was that his part-memoir, part-popular science book contained far more about the pace, people and progress of science than could ever be gleaned from…

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To GM or not to GM?

It’s not about the science. In 1983, a gene from Agrobacterium (a plant-infecting bacterium) was successfully inserted into a plant cell, marking a ‘coming-of-age’ moment for plant genetic engineering. The resulting possibilities seemed endless; pest-resistant, self-fertilising and nutritionally-fortified crop varieties. But relatively little of this technology has been implemented on a global scale. Casual viewers…

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A Global Threat to Humanity: Anti-Microbial Resistance

Antimicrobial resistance (AMR) is spreading at an alarming rate, yet the antibiotic industry is only shrinking—could a pre-antibiotic era return as our future? Antimicrobials revolutionised medicine. Before antibiotics, the average life expectancy was 47 years. Infections such as pneumonia could easily be fatal, and to put it bluntly, a scratch could kill. There is no…

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